Ministry of Hemp

Ministry of Hemp

America's leading advocate for hemp

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Full Spectrum CBD VS. CBD Isolate: Which CBD Should I Take?

This article breaks down two common terms used to describe CBD products: full spectrum and CBD isolate. While some preliminary research suggests full spectrum CBD is better, CBD isolate still has many uses.

This article breaks down two common terms used to describe CBD products: full spectrum and CBD isolate.

The cannabis industry is one of the most exciting and fastest growing in the natural health sector. With laws around the world relaxing on the plant and its commercial uses, we’ve seen some incredible new hemp products come to market.

The most popular of them all at the moment is cannabidiol oil, or more commonly known as CBD oil. With so many new and different CBD oil products available, the choice of which one to go with can be difficult and confusing. With terms like whole plant extract, full spectrum, broad spectrum and isolate. This article will break down the difference between two terms you’ll commonly see, full spectrum CBD oil and CBD oil isolate, in order to help make your decisions easier.

A row of identical looking bottles of CBD oil, each with a dropper top. Not all CBD oil is made the same, and the terminology can be confusing, such as the difference between full spectrum CBD and CBD isolate.

Not all CBD oil is made the same, and the terminology can be confusing, such as the difference between full spectrum CBD and CBD isolate.

Cannabidiol (CBD) is a non-intoxicating molecule found in the cannabis plant. It is one of many cannabinoids that can be extracted from the cannabis plant but it has become commercially popular beyond the others due to its wide medical applications and accessibility. As CBD does not give the consumer the famous high that psychoactive cannabis (“marijuana”) is known for, it is more readily available online and in shops. It is usually derived from hemp, the name given to cannabis plants with less than 0.3% THC which can be mass grown for CBD oil.

WHAT IS FULL SPECTRUM CBD OIL?

The cannabis plant contains hundreds of different phytochemicals including cannabinoids, terpenes, and other compounds. Full spectrum CBD or hemp oil generally refers to products that not only contain CBD but contain the other plant molecules as well. This version of CBD oil is minimally refined, leaving most of the cannabinoids and terpenes intact and in the oil.

Full spectrum, sometimes also called “whole plant,” means the full plant extract is included. Full spectrum provides more of the plant’s molecules in ratios and amounts that nature intended.

While there is still more research to be done, there are indications that show cannabinoids and terpenes work together to influence each other. This synergistic effect is called the entourage effect and has seen CBD work with THC to reduce the effects of a high and CBD to influence ones own cannabinoid receptors.

WHAT IS CBD ISOLATE?

Cannabidiol alone has been the subject of a lot of research as it stands out from the rest with what seems to be the widest therapeutic value.

CBD isolate products are generally labeled as being 99 percent or more pure CBD depending on the form they come in. As the name suggests, these products have been isolated down to just the CBD molecule. They have no other active ingredient and just aim to deliver therapeutic doses of CBD, isolated from the other cannabinoids and terpenes.

CBD isolate products often come as a white powder or a mix with a carrier oil such as MCT oil for improved absorption.

COMPARING FULL SPECTRUM CBD VS CBD ISOLATE

CBD and the other cannabinoids have therapeutic benefits to humans thanks to our endocannabinoid system, a series of cannabinoid receptors (CB1 and CB2) throughout the entire body. These receptors react to the cannabinoids our bodies produce which are molecularly very similar to the cannabinoids from cannabis and hemp.

Two different colored vials of hemp extract sit on a bed of hemp leaves. Full spectrum CBD contains more cannabinoids and other natural compounds, while CBD isolate may be better for people who need a strong dose of just cannabidiol.

Full spectrum CBD contains more cannabinoids and other natural compounds, while CBD isolate may be better for people who need a strong dose of just cannabidiol.

Full spectrum CBD oil products have the advantage of containing many different cannabinoids and terpenes and the potential for a wider health reach. = A recent study indicated the synergistic effects of a full spectrum CBD oil were superior to an isolate in the effective treatment of inflammatory conditions. Terpenes alone have shown incredible potential for human health and should not be disregarded.

CBD isolates do allow users to easily get large amounts of CBD and know how much they’re getting. With the growing amount of evidence behind CBD and CBD alone it should definitely not be overlooked as a potential for so many conditions such as anxiety, pain, inflammation, diabetes, depression and more.

Some people find the taste of hemp extract unpleasant, which may mean they should try a CBD isolate (or another method of taking CBD such as CBD capsules or gummies). The lack of flavor might also make isolate a better choice for cooking with CBD or mixing into some CBD cocktails. CBD isolate powder can also be an appealing option for making CBD products for personal use, such as homemade CBD massage oil.

Isolates can sometimes be more expensive than full spectrum CBD. Isolates undergo more extensive refinement and require more plant matter in order to get high levels of isolated cannabidiol.

GET TO KNOW DIFFERENT CBD PRODUCTS

It’s hard to know which one is best for you without trying them both and see how you react. Different ailments might react differently a full spectrum CBD than to a CBD isolate. We recommend trying a variety of products and assessing how you feel. If you’re finding your condition is not reacting significantly to a full spectrum oil then trying an isolate may be the way to go, and vice versa.

Bottles and a beaker containing amber colored CBD oil arranged with hemp buds, sitting on a reflective tabletop surface. Some research suggests full spectrum CBD can be more effective, but consumers should experiment with a variety of CBD products. Some research suggests full spectrum CBD can be more effective, but consumers should experiment with a variety of CBD products and, when possible, consult with a supportive medical professional for more advice.

Some research suggests full spectrum CBD can be more effective, but consumers should experiment with a variety of CBD products and, when possible, consult with a supportive medical professional for more advice.

It’s still very early in the days of cannabis research but there is a strong case for the therapeutic benefit of a less refined full spectrum hemp extract with more of the plant compounds intact. There are so many beneficial health possibilities waiting to be unlocked by further studying the combinations of these compounds found in hemp and cannabis.

Remember, it’s not all about the amount of CBD per serving you see on a bottle. A higher CBD product isn’t necessarily superior to a full spectrum oil. Leaving the plants extracts closer to the way nature intended could be a better option for most people.

 

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Using CBD Gummies For Anxiety And Depression

CBD gummies can make a valuable daily supplement for people struggling with anxiety and depression. Some consumers report they offer long lasting relief to many of their symptoms, and some science supports this too.

Are anxiety and depression keeping you from living a fulfilled life? CBD is an all-natural health supplement with anti-anxiety properties that could help improve your daily life. Learn about the health benefits of CBD Gummies and how they could help you with symptoms of anxiety and chronic stress.

Mental health problems are at an all-time high and many people feel underserved by traditional psychiatric medicines. Studies on CBD reveal that it could help with anxiety, depression, and other mental health issues.

Chronic stress can be caused by a multitude of factors. How we respond to stress could be the key to reducing anxiety and preventing the risks associated with mental health disorders.

In this article, you’ll learn the benefits of CBD gummies on anxiety, what doses of CBD are most effective, how to find quality CBD, and more.

CBD OIL: SAFETY & LEGALITY

CBD, or cannabidiol, is an all-natural supplement that can offer a wide range of health benefits for a number of different issues, including mental health problems such as anxiety or depression.

CBD oil in a glass jar sits on a table top near a hemp bud. CBD oil derived from hemp can be legally obtained in all 50 states.

CBD oil derived from hemp can be legally obtained in all 50 states.

CBD sold online is typically derived from hemp. Both hemp and marijuana are two types of the same species of plant known as, cannabis. And although hemp is very similar to marijuana, it is also very different.

Unlike marijuana, the hemp plant contains less than .3% THC, which is the main psychoactive compound found in cannabis.

That means that CBD doesn’t get you high and does not cause the psychotropic effects associated with marijuana and THC.

Studies evaluating the safety of CBD have shown that the compound is extremely safe, even in high dosages. However, there are some things you should consider when taking cannabidiol.

The most severe, but very uncommon side effects of CBD are sedation and fatigue. Cannabidiol can also lower blood pressure and change the way your body processes some types of medications.

CBD is legal in all 50 states under the 2014 Farm Bill upheld by the 2018 HIA vs. DEA ruling of the 9th Circuit Court of Appeals.

HOW DOES CBD WORK?

Cannabidiol is just one of over a hundred compounds in hemp, called cannabinoids, being studied and used for therapeutic benefits.

CBD works supporting the body’s natural endocannabinoid system; a network of biochemical compounds and receptors specialized to maintain balance in nearly every aspect of health and wellness.

The hemp compound fits perfectly into specialized receptors, called cannabinoid receptors, which control different bodily functions that influence health.

An illustration of neurons firing in a human head. The unique effects of CBD in the brain lead to a host of healing benefits from this popular supplement.

An illustration of neurons firing in a human head. The unique effects of CBD in the brain lead to a host of healing benefits from this popular supplement.

Our bodies produce compounds that are identical to the cannabinoids found in hemp, which is why CBD fits like a lock and key in our receptor cells.

These identical compounds produced by the body are called, endocannabinoids, short for endogenous cannabinoids.

CBD interacts with the endocannabinoid system by binding with cannabinoid receptors such as CB1, CB2, and others.

Research shows that this vital health system is an integral part of the not only the sleep process, but also emotional stability, mental health, and many other aspects of wellness.

CBD ANXIETY & DEPRESSION STUDIES

Recent data revealed that 1 in 5 Americans took some type of psychiatric medication recently, meaning anxiety and depression are much more common than we’d like to talk about.

Most of what we know about CBD and mental health comes from animal studies and small-scale human experiments. However, a growing body of evidence along with thousands of anecdotal reports suggests CBD can improve symptoms of anxiety and mood disorders.

An older man in a plaid shirt clutches his head in anguish. Today, CBD is used to relieve symptoms of numerous conditions, from anxiety and mental illness to chronic pain.

Today, CBD is used to relieve symptoms of numerous conditions, from anxiety and mental illness to chronic pain.

Chronic stress is often a primary trigger of anxiety, and animal studies show us that CBD can calm the stress-response and nervous system. Further experimentson mice and humans show us that CBD also has properties that can relax the muscles and blood vessels, even during stress. It also exhibits a natural calming effect on the mind, which could aid the onset of sleep and reduce symptoms of anxiety or depression.

Researchers believe this effect occurs when CBD binds with the 5-HT1A neuro-receptor. This receptor is essentially like a signaling hub in the brain for emotions and is also the main target of most modern antidepressants.

One of the most notable studies on CBD’s effects on anxiety disorders in humans comes from a trial on the fear of public speaking. Compared to a placebo, CBD reduced the physical markers of stress-related anxiety and participants reported fewer symptoms of the phobia.

Several peer-reviewed analysis also now confirm and validate the study’s results indicating CBD as a potential drug for anxiety disorders.

USING CBD GUMMIES FOR ANXIETY & DEPRESSION

Taking CBD for sleep, anxiety, and depression can be as simple as snacking on a few tasty Gummies once or twice per day.

CBD-infused Gummies are made using all-natural ingredients and non-GMO, organic CBD hemp concentrate produced by super-critical CO2 extraction. Similar to taking chewable vitamins, Gummies offer a safe, effective way to easily take cannabidiol as a daily supplement. You can find them available in a range of potencies from 5mg-25mg and are typically sold in 30-60 count bottles.

Assorted rainbow gummy bears spill from a plastic bottle. When it comes to CBD dosing, start small and increase gradually after you feel the supplement's effects. CBD gummies come in a variety of dosages, typically offering between 5mg and 25mg per candy.

CBD gummies come in a variety of dosages, typically offering between 5mg and 25mg per candy.

CBD is non-toxic and non-intoxicating, which means that you can’t overdose from eating too many gummies. Unlike with THC edibles, you don’t have to worry about experiencing anxiety or paranoia from eating too many CBD Gummies.

There is no exact dosage of CBD for any particular condition or ailment, but it’s generally recommended to begin taking CBD gummies in smaller, low dosages. You can increase the dosage as needed once you’ve observed how CBD may affect your symptoms.

Similar to eating grapefruit, CBD could alter the way your body metabolizes certain types of medications. Always consult with your doctor first for treating serious health conditions.

WHY DO PEOPLE CHOOSE CBD GUMMIES OVER OTHER FORMS OF CBD?

When it comes to cannabidiol, if all things are held constant (like product quality) the major differences in products boils down to administration/consumption methods. For example, tinctures are dropped under the tongue and the CBD is absorbed sublingually. Gummies however, are eaten and the CBD is absorbed through the digestion process.

The most popular reason for using gummies over tinctures or other forms of CBD is by far, the taste. Many people find the earthy flavors of oils to be unappealing. CBD gummies however, taste great. People also find that using the gummies is a little more discreet than other forms, and they can administer their CBD in public more freely.

When comparing the effects of tinctures over edibles, consumers typically notice a faster and stronger effect when using tinctures. For anxiety or depression issues, they can be great in high-stress moments where the onset of panic begins, using CBD oil sublingually might help elevate issues in moments, rather than waiting for the CBD to be digested.

A closeup of rainbow gummy bears in a pile. Some anecdotal reports suggest CBD gummies offer longer lasting but milder effects than some other forms of CBD.

Some anecdotal reports suggest CBD gummies offer longer lasting but milder effects than some other forms of CBD.

However, consumers do report that using CBD gummies and edibles for anxiety is extremely effective as well. This is because edibles tend to have a “milder” effect, but last longer as the CBD goes through the digestion process to be absorbed into the bloodstream. People with anxiety issues tend to notice that they handle the rigors and stresses of daily life much better throughout the day when using edibles over tinctures.

FIND QUALITY CBD ONLINE

How do you find the best CBD retailers online?

First, always make sure that a retailer’s website is secured by checking the URL in the browser for the little SSL lock. If the site is not secure, your personal information could be at risk.

Second, always ask the retailer for the 3rd party lab tests for any CBD products you are interested in. These are the tests that analyze the chemical composition of a product or CBD extract and will prove its purity and concentration. This test will also indicate whether or not a CBD product contains any amount of THC, which is important if you are concerned about drug testing.

Thanks for reading! If you’ve enjoyed this article, please share it with others who may also find it helpful!

 

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How Endurance Athletes Use CBD: CBD Oil Helps You Go The Extra Mile

Marathon runners, triathletes, cyclists, and other such athletes push their bodies and minds to the limits, and many of them find themselves in states of constant physical pain or mental exhaustion. CBD can help them feel better and go further.

Every day, an increasing number of endurance athletes use CBD to go further and feel better.

The potential benefits of CBD and its balancing properties are just beginning to gain recognition. CBD can help almost anyone who has general pain, anxiety, or other day-to-day physical and psychological issues. Many of us undergo a lot of physical and mental stress in our daily lives, and endurance athletes are no exception. Marathon runners, triathletes, cyclists, and other such athletes push their bodies and minds to the limits, and many of them find themselves in states of constant physical pain or mental exhaustion.

THE MANY WAYS ENDURANCE ATHLETES USE CBD

As CBD has become more prominent, it’s become more and more recognized in the world of athletics. The biggest potential benefits for endurance athletes are CBD’s potential to reduce inflammation and stress or anxiety, improve recovery time, and even control appetite.

A silhouette of a runner jogging during a sunrise. Distance runners, triathletes, professional cyclists and other endurance athletes use CBD because it helps them perform better and longer.

Distance runners, triathletes, professional cyclists and other endurance athletes use CBD because it helps them perform better and longer.

Endurance Athletes Use CBD To Reduce Inflammation and Soreness

For athletes who put a lot of miles on their bodies, inflammation is one of the biggest concerns. Constant use of muscles and joints can cause inflammation and soreness. CBD is a natural anti-inflammatory that also can protect cells from oxidative damage. Studies have shown that CBD might be an alternative to over-the-counter pain medicines like Advil and Tylenol.

CBD Can Increase Energy

When taken in smaller doses, CBD actually activates the same adenosine receptors that caffeine does, providing a boost of energy. This can be great for training or race days that might seem like too much otherwise. The boost of energy is just one way that CBD might help improve recovery times.

CBD Will Reduce Stress and Anxiety

CBD has also shown potential in reducing stress and anxiety. This is due to its ability to regulate the endocannabinoid system. Essentially, CBD acts on the cannabinoid receptors that are responsible for responses to stress. Some athletes have found that CBD helps them recover from the stress of making time for training in their already busy schedules and from their workouts. It can also be helpful for race/event days to calm pre-race nerves or to help fall asleep the night before. Since our bodies don’t repair themselves as well when under stress, this benefit of CBD may help endurance athletes recover from heavy training or injuries more easily.

Control Appetite Your Appetite With CBD

Finally, CBD might help control your appetite. If you are on a strict training diet, CBD has been shown to not only slow appetite, but also help feel full for longer. This could be a great benefit for athletes who are trying to put the healthiest foods into their bodies without overeating. Some studies have even shown that CBD helps boost metabolism and increase the body’s ability to burn fat.

WHICH ENDURANCE ATHLETES USE CBD?

Athletes who are constantly training or competing may find that CBD provides relief from the stress of the endurance world. Triathletes, distance runners, cyclists, and athletes who do similar sports will likely appreciate CBD’s potential as a painkiller and anti-inflammatory.

Cyclists race on a roadway in a tight pack, wearing sponsored pro cyclist gear and helmets. Some endurance athletes use CBD to reduce their dependence on pharmaceutical painkillers to relieve the soreness of workouts.

Some endurance athletes use CBD to reduce their dependence on pharmaceutical painkillers to relieve the soreness of workouts.

While scientific studies on CBD’s potential athletic benefits are yet to be done. Anecdotally, many endurance athletes say that they have stopped using all painkillers in favor of CBD. Others say that CBD helps them focus and improves their stamina when taken before running or other forms of exercise.

And the benefits aren’t just there for endurance athletes: CBD might help athletes who participate in many other sports. Preliminary research suggests CBD is a neuroprotectant. That means CBD could help the brain recover from concussions. Soccer players, football players, and other athletes who might get hit in the head could find CBD useful.

BEFORE YOU BUY CBD

CBD is still being researched, so there are not a lot of regulations on how it is produced.

If you are interested in trying CBD, the most important thing to do is research whether CBD is legal where you live. If so, you can begin your search for a CBD company. You’ll probably find a few options online. Like with anything on the internet, do your research on these companies.

A reputable CBD company will have its products tested by third parties, who will check that the product is, in fact, what it claims to be. CBD companies should provide the results of the tests; and if they don’t, it’s best to look elsewhere. And, while there is evidence that CBD can help with a variety of ailments, there are no conclusive proofs about it yet. Make sure to avoid CBD companies who promise to cure every problem you are experiencing.

Otherwise, whether you are an athlete or not, we hope that if you try CBD, you are pleased with the outcome!

 

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CBD Myths vs. Facts: The Truth About Hemp-Derived CBD (VIDEO)

Despite its popularity, there are still myths and misconceptions around hemp-derived CBD oil. Our latest video takes a look at the truth behind 5 CBD myths.

CBD myths continue to proliferate despite the growing popularity of this beneficial nutritional supplement.

Hemp’s popularity is booming in America, and thousands of people have discovered the benefits of CBD. However, a great deal of stigma and confusion remain. In our latest video, we take a look at 5 common myths about CBD.

  • CBD Myth #1: CBD will get you high.

Hemp is not marijuana. Hemp-derived CBD products have less than 0.3% THC and will not result in feelings of intoxication. While it’s possible to have side effects from CBD, as long as you use a quality CBD tincture, these are rare and usually minimal.

  • CBD Myth #2: Urinalysis tests only test for THC.

While hemp extracts predominantly contain CBD, they are not completely THC free. It is possible to fail a drug test from taking CBD supplements.

  • CBD Myth #3: You need THC to activate CBD.
Despite its growing popularity, there are still myths and misconceptions around hemp-derived CBD oil. Our latest video takes a look at the truth behind 5 CBD myths.

Despite its growing popularity, there are still myths and misconceptions around hemp-derived CBD oil. Our latest video takes a look at the truth behind 5 CBD myths.

Hemp contains numerous naturally occurring compounds, called cannabinoids, that interplay to create beneficial effects. CBD can work alone, but when it interacts with other cannabinoids to greater effect, this is known as the “entourage effect.”

  • CBD Myth #4: Hemp-derived CBD is not as effective as CBD from marijuana.

CBD is CBD, no matter the original source. The human body does not recognize whether CBD is sourced from medical cannabis or hemp.

CBD Myth #5: CBD Products are illegal since they come from cannabis.

According to the analysis of numerous hemp experts, the 2014 Farm Bill and other laws and precedents make it legal to possess and distribute CBD oil in the U.S.

Sponsored by our friends at PlusCBD Oil.

 

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Other Cannabinoids Revisited: More Natural Chemicals Found In Hemp

In this article, we continue our look at other cannabinoids found in hemp and cannabis. This time we examine four more cannabinoids — CBC-a, CBDV, CBG-a, and CBCV — and how they can benefit humanity.

In this article, we continue our look at other cannabinoids found in hemp and cannabis.

In July, we published our first look at different naturally occurring cannabinoids that are less well known than THC and CBD. There, we discussed the benefits of CBG (Cannabigerol), CBC (Cannabichromene), THCV (Tetrahydrocannabivarin), and CBN (Cannabinol). The article sparked some good discussion on social media and we’re hoping for the same with this one as we follow up with four more cannabinoids of note.

Preliminary research into the various other cannabinoids found in hemp and cannabis reveals that there's more to healing than just THC & CBD. Photo shows a hemp leaf surrounded by beakers of green fluid in a lab.

Preliminary research into the various other cannabinoids found in hemp and cannabis reveals that there’s more to healing than just THC & CBD.

This time, we’re going to discuss CBC-a (Cannabichromenic Acid), CBDV (Cannabidvarin), CBG-a (Cannabigerolic Acid), and CBCV (Cannabichromevarin). While these cannabinoids do show promise, they seem to be a lower priority for researchers. But hopefully, as researchers and scientists continue studying other cannabinoids, more information will become available on these lower tiered compounds.

CANNABICHROMENIC ACID (CBC-A)

The first cannabinoid we’re going to discuss is CBC-a (Cannabichromenic Acid).

CBC-a is the precursor to one of the most highly sought after cannabinoids, CBC (Cannabichromene). Like four other cannabinoids, CBC-A appears in the cannabis plant through decarbing. CBCA is non-psychoactive like CBD and has strong antimicrobial and analgesic (pain-relieving) properties. According to Maximum Yield, the most abundant levels of CBC-a are found in tropical strains of psychoactive cannabis (“marijuana”) with much lower levels found in other types of cannabis. According to current research, plants begin secreting cannabichromenic acid in the early seedling stage, before they create THC (Tetrahydrocannabinol). CBC-a can be converted to CBC through an aging and heating off the acid thru decarboxylation.

CBC-A Benefits:

  • Antimicrobial and analgesic properties
  • Anti-viral and anti-inflammatory

CANNABIDVARIN (CBDV)

Next up is CBDV (Cannabidvarin).

Like CBCA and most other cannabinoids we’ve discussed, CBDV is a non-psychoactive cannabinoid that has a similar makeup to CBD. Cannabis or hemp strains with higher levels of CBD tend to have higher levels of CBDV as well. Currently there hasn’t been much research on CBDV. Preliminary research shows that CBDV reduces nausea and seizures.

A researcher studies a hemp plant in a field. Hemp and cannabis contain numerous other cannabinoids beyond THC & CBD. These include CBC-a, CBDV, and many more.

Hemp and cannabis contain numerous other cannabinoids beyond THC & CBD. These include CBC-a, CBDV, and many more.

CBDV Benefits:

  • Anti-nausea. A study in 2013 by the British Journal of Pharmacology researched the potential of CBDV and THCV’s anti-nausea’s effect on rats’ brains. Researchers concluded that both cannabinoids “may have potential in reducing nausea.” Just by the quote alone, it’s apparent more research needs to be done.
  • Anti-seizures. Initial studies show that CBDV acts in a similar way to anti-convulsive medication Capsaicin, which targets the TRP channels (transient receptor potential channel) to combat the gradual process of brain development epilepsy. In fact, an Italian research team found that both CBDV and Capsaicin dephosphorylated TRPV1. CBDV’s effects on TRP channels are being studied to fully understand this cannabinoids anticonvulsive ability. One pharmaceutical company, GW Pharmaceuticals, is actively developing CBDV products for research in clinical trials. They are currently in a phase 2- trial CBDV product under the name GWP42006 that they’re hoping to be approved in treating adults with epilepsy.

CANNABIGEROLIC ACID (CBG-A)

The next in our list of other cannabinoids is CBG-a (Cannabigerolic Acid).

CBGA is considered the “cannabinoid stem cell.” Without CBGA, the amazing health benefits of THCa/THC, CBDa/CBD, CBCa/CBC, and CBG would not exist! These other cannabinoids form through biosynthesis, where chemicals combine to form new compounds. Studies show that industrial hemp contains high levels of CBGa, with some plants carrying up to 94% CBG!

CBG-A Benefits:

      • Analgesic. CBGa has been found to be an analgesic, meaning it provided pain relief.
      • Anti-bacterial. CBGA delays the growth of new bacteria.
      • Anti-inflammatory. CBGa reduces inflammation systematically.
      • Biosynthesis. Without CBGa the medicinal benefits of the other cannabinoids wouldn’t exist. This is important. So much so that scientists aren’t directly studying this cannabinoid. Instead, funding and research are all going to better understand how the biosynthesis itself works.

CANNABICHROMEVARIN (CBCV)

The last other cannabinoid we’re going to talk about is CBCV (Cannabichromevarin).

A researcher in a lab coat studies the leafy flower top of a hemp plant in a field. Research into other cannabinoids helps us understand how this amazing plant can benefit humanity.

Research into other cannabinoids helps us understand how this amazing plant can benefit humanity.

CBCV was first discovered in 1975 when researchers at the University of Nagasaki in Thailand islolated the compound from the cannabis plant. This cannabinoid is the precursor to Cannabichromene (CBC). Cannabis strains with lower levels of THC and CBD often have higher levels of CBCV.

CBCV Benefits:

  • Anti-convulsive.  One of the major benefits of CBCV is its anticonvulsant properties. Researchers from the Regents of the University of California have a patent on an anticonvulsant drug for infants dealing with seizures. Although the primary compound in the drug is CBD, the University of California mentions both CBCV and CBC in the patent as well.
  • Anandamide (AEA) reuptake inhibitor. Anandamide is a naturally occurring cannabinoid in humans. Researchers found that CBCV blocks Anandamide’s absorption by our brain and keeps it working for longer in our bodies.
  • Very similar medical benefits to CBC, CBCV is a powerful anti-inflammatory, antidepressant, antibiotic, analgesic and antifungal and may be beneficial for patients suffering from:
  1. Chronic pain
  2. Major depression
  3. Inflammation
  4. Cancer
  5. Epileptic seizures
  6. Crohn’s disease
  7. Alzheimer’s disease

WAR ON DRUGS INTERFERES WITH RESEARCH INTO OTHER CANNABINOIDS

In the span of two articles we shared 8 different cannabinoids, plus CBD and THC, which we discuss at great lengths in other articles. That’s 10 of the most researched and medically beneficial cannabinoids!

This time around we weren’t able to go as in-depth as we normally would in these types of articles because there just wasn’t enough information on these other cannabinoids just yet. We know scientists believe there are over 100 cannabinoids in the cannabis plant. Research and funding opportunities are still very limited. Cannabis and hemp are both classified as a Schedule I drug by the Drug Enforcement Administration. This classification means the agency refuses to acknowledge that these plants have any medical benefits, despite the evidence to the contrary.

Until this changes, the war on drugs limits our knowledge of the benefits of these miraculous plants. Fortunately, we believe that this will soon change for the better.

In the meantime, read and get to know the cannabinoids we shared, and learn about how they might help people like you.

 

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Hemp In Space: Researchers Send Hemp Plants To International Space Station

Hemp in space sounds like a science fiction dream. Earth researchers will soon begin growing hemp in space on a tiny laboratory aboard the International Space Station, created by Space Tango in partnership with Anavii Market.

Hemp in space sounds like a science fiction dream. It will soon to be an exciting new reality thanks to a partnership of terrestrial firms hoping to learn about the effects of microgravity on the crop.

Space Tango, a start-up business from the heart of Kentucky seeks to harvest hemp in space. Co-founder and chairman, Kris Kimel, wants to lean about how the biology and quality of the crop will develop without the influence of gravity. The goal is to see if the medicinal value of cannabinoids prospers on this new frontier and to offer unique CBD products to the public.

Anavii Market is partnering with Space Tango on their journey into this new frontier. Anavii Market is an online CBD marketplace that seeks to improve quality reliability in the industry. Their goal is to provide a trusted source of CBD to the public.

A photo of the International Space Station in orbit over earth, Space Tango and Anavii Market will soon begin experimenting with the immense potential of growing hemp in space.

Space Tango and Anavii Market will soon begin experimenting with the immense potential of growing hemp in space. (Photo: NASA)

We caught up with Kimel to learn about Space Tango’s hemp project.

He told us, “We’re primarily interested in looking at how biomedical … systems operate and change when removed from the gravity well of earth.”

WHAT WE KNOW ABOUT GROWING HEMP IN SPACE

Prior to Space Tango, Kimel was the founder and president of the Kentucky Science and Technology Corporation (KSTC), “which is where this notion of looking into space and microgravity kind of germinated.” As his interest grew, he left the company and moved over to Space Tango full time.

After nearly a decade of research on this new frontier, Kimel tells us there’s still so little they know and so much to learn when it comes to how plants develop in a gravity stress-free environment. Since hemp has had such little research within the last century and only recently has had its doors opened to scientists, Space Tango remains optimistic in breaking through new discoveries.

Kimel and his team are aware that principle biological systems (i.e. cells, organisms) become scrambled grown without gravity. In turn, this “opens up new pathways, new understandings, of those systems that you’d never see on earth.” Prior to their experiments with hemp, they’ve developed medical implants which can only be manufactured in space.

HEMP IN SPACE: HOW IT ALL WORKS

Permanently installed on the International Space Station are two research and development laboratories for the Space Tango team. Within each of those labs are 21 component parts of operations known as CubeLabs. The purpose of these modules is to reduce the amount of hands-on interaction required to grow organisms in space. They’re about the size of a “Kleenex tissue box and fully equipped with microtechnology.”

CubeLabs function to:

  • Operate independently.
  • Supply a responsive payload.
  • Process data and images to earth in real-time.
  • Reduce application development life-cycle.
  • Decrease astronaut interplay.
Space Tango's module on the International Space Station features multiple "CubeLabs," modular research labs each the size of a box of tissues. The firm will soon be growing hemp in space in one of these labs.

Space Tango’s module on the International Space Station features multiple “CubeLabs,” modular research labs each the size of a box of tissues. The firm will soon be growing hemp in space in one of these labs. (Photo: NASA)

The purpose of these CubeLabs is to find medical solutions which can be applied back here on earth. This is also Space Tango’s primary interest in cultivating hemp. “Our science team has looked at recent developments of CBD and we think an enhance in cannabis and CBD holds great potential for treatment of serious conditions such as epilepsy or migraine headaches.”

Furthermore, due to cannabis’s entanglement in legal issues, new research is constantly being developed. Kris believes him and his team have the ability to discover aspects of CBD and marijuana which aren’t currently there. He tells us, “What we do know in combination with microgravity holds very great potential.”

THE FUTURE OF HEMP IN SPACE

If these experiments go as planned, Space Tango hopes to offer CBD products to both consumers and the medical industry. The first experiments with hemp in space are scheduled to begin in either January or February of 2019. Due to regulations and policies with both the state and NASA, there are some legal actions Space Tango still needs to take before allowing hemp to enter this new frontier. However, Kimel informs us that Space Tango is committed to making sure they go about the experiments the right way.

So, how do these experiments work?

“Obviously, things are more difficult and complicated in space,” Kimel tells us. “Once the technology is designed, we install it into our labs and, from there, it takes about four to six weeks and then they’re brought back to the lab for analysis.”

Through these analyses, Space Tango believes they can find treatment for certain diseases which you couldn’t find here on earth. Kimel claims, “you get a better resolution with certain kinds of drugs in space.”

“Our ultimate goal is to have a transformational benefit of life on earth,” he concluded.

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Fibromyalgia, Migraines & The Science Of Clinical Endocannabinoid Deficiency

First proposed by Dr. Ethan Russo, Clinical Endocannabinoid Deficiency could contribute to numerous painful conditions from fibromyalgia to IBS to migraine. This would help explain why cannabis and hemp help so many people with these conditions.

A theoretical syndrome, clinical endocannabinoid deficiency, could provide new insight into painful conditions suffered by millions.

Scientific advancements have helped us to find working treatments for countless debilitating conditions. However, there are some illnesses that continue to prove notorious and mysterious, with no known causes or cures. Research into the endocannabinoid system (ECS), a network in the body influenced by plant-derived cannabinoids, has provided medical experts with a fresh perspective on ailments such as fibromyalgia, irritable bowel syndrome (IBS) and migraines.

Dr Ethan Russo, a professional neurologist and cannabis researcher, first published the concept of a spectrum disorder in 2004. He first began working on the idea of dysregulation in the ECS in 2001. Both doctors and patients have noticed that cannabis and CBD oil seem to benefit people with these conditions. Russo has proposed that the effectiveness of cannabinoid medicine in the trio of aforementioned conditions can be explained by Clinical Endocannabinoid Deficiency (CECD).

A white paper cutout of a human head, missing a puzzle piece shaped hole, sits on a wooden surface. The puzzle piece, colored red, sits nearby. Though still theoretical, clinical endocannabinoid deficiency could be a common contributor to numerous conditions, from fibromyalgia to migraines.

Though still theoretical, clinical endocannabinoid deficiency could be a common contributor to numerous conditions, from fibromyalgia to migraines.

INTRODUCING CLINICAL ENDOCANNABINOID DEFICIENCY

For the ECS to function efficiently, the body must produce endocannabinoids (naturally occurring, cannabis-like chemicals) such as anandamide (AEA) and 2-Arachidonoylglycerol (2-AG).

However, studies have found that some people have lower endocannabinoid levels than others, which brings about health complications. There is an increasing body of clinical research which shows anxiety to be associated with reduced anandamide levels, and major depression to be linked with reduced 2-AG levels. When the body is unable to produce endocannabinoids in the concentrations required, chemical imbalances occur, which leads to illness.

Cannabinoid receptors interact with both endocannabinoids and cannabinoids, with the plant-derived compounds able to mimic endocannabinoids or otherwise influence them for ECS regulation. Therefore, it is logical that a cannabinoid treatment could effectively remedy CECD.

Russo’s latest significant update on his CECD research came in 2016, with a paper that continued to build on the concept, incorporating available clinical evidence. This followed an earlier 2008 release.

FIBROMYALGIA AND CLINICAL ENDOCANNABINOID DEFICIENCY

Medical researchers have been unable to come up with a definite cause for fibromyalgia. Patients suffer from an array of debilitating symptoms that have a significant effect on quality of life. These symptoms include chronic deep muscle and tender point pain, impaired cognitive function (or “fibro fog”), headaches, sleeping difficulties and restless leg syndrome. According to the Anxiety and Depression Association of America, 20 percent of fibromyalgia patients experience one of or both of these mental health disorders. Typically, this is a result of the pain and fatigue caused by the condition. In 2011, a study found that CBD could reduce anxiety beyond placebo levels, with patients given a 600mg dose administered via CBD capsules.

Moreover, several symptoms of fibromyalgia are indicative of ECS dysregulation — for instance, inflammatory conditions occur due to problems with immune system response, which is modulated by the ECS and specifically the CB2 receptor. Studies have also found that serotonin levels are affected in fibromyalgia patients, which may be noteworthy considering CBD is an agonist of the 5-HT1A receptor.

MIGRAINES AND CLINICAL ENDOCANNABINOID DEFICIENCY

Around 39 million Americans are affected by migraines, according to the Migraine Research Foundation. Migraines can cause dizziness, nausea, numbness or tingling in the face and other unpleasant symptoms. Research has shown that migraine sufferers have “statistically significant” differences in anandamide levels in cerebrospinal fluid, which is found in the brain and spinal cord.

A woman clutches her head in pain, as if suffering from a migraine. Migraine sufferers have been shown to have lower levels of anandamide, a naturally occurring chemical found in all people that's similar to those found in cannabis and hemp.

Migraine sufferers have been shown to have lower levels of anandamide, a naturally occurring chemical found in all people that’s similar to those found in cannabis and hemp.

Russo found that endocannabinoid system changes could help to alleviate migraines in his 2004 research. The main finding was that anandamide, a key neurotransmitter in the ECS, heightens the effectiveness of the 5-HT1A receptor while inhibiting the 5-HT2A receptor. This could help with treating acute migraines and as a preventative treatment. Furthermore, the results showed that several cannabinoids exhibited anti-inflammatory properties and dopamine-blocking effects.

The light and sound sensitivity that results from migraines may be due to an overactive nervous system. The ECS is renowned for regulating such imbalances (Russo, 2016). Some have suggested that the root cause of migraines can be traced back to the trigeminovascular system, which brings blood to the brain. Studies have shown that endocannabinoids can influence this system. Migraines and cluster headaches may be best managed with a treatment that is an agonist of the CB1 receptor.

In the case of migraines, one study found that while a CBD and THC treatment was not necessarily more effective than existing anti-migraine treatments, the side effects were significantly reduced.

Fascinatingly, cannabis was a common treatment for migraines in Europe and North America from the mid-1800s until the 1940s, a time when the herb was being prohibited around the globe.

NEXT STEPS IN CANNABINOID RESEARCH

As governments all over the world look into the benefits of medical cannabis, the number of high-quality studies being carried out in clinical settings is sure to increase.

With time, we should get an in-depth look at the potential of cannabinoids as a treatment for fibromyalgia, migraines and other illnesses. As our understanding of the ECS deepens, we may learn more about the wide-scale implications of dysfunction in the system.

A gloved scientist with a vial of CBD and a hemp leaf. 'Full spectrum' extracts contain more cannabinoids, terpenes, and other beneficial chemicals found in hemp & cannabis.

A gloved scientist with a vial of CBD and a hemp leaf. ‘Full spectrum’ extracts contain more cannabinoids, terpenes, and other beneficial chemicals found in hemp & cannabis.

Furthermore, more research needs to be done on the possible interactions cannabinoids have with receptors outside of the ECS and the effects this may have on the body.

CLINICAL ENDOCANNABINOID DEFICIENCY SHOWS HOW MUCH WE HAVE LEFT TO LEARN

It’s essential to bear in mind that the work of Dr Russo and others on CECD is at the forefront of cannabis science, and we still have plenty to learn about the endocannabinoid system, the effects of its dysregulation, and the genuine potential of cannabinoid-based medicines for treating notoriously complicated conditions such as fibromyalgia.

However, the theory has certainly fleshed out since 2004. There are studies that suggest medical cannabis and CBD can have a therapeutic effect for certain conditions. But in his 2016 paper, Russo noted that contradictions in CECD research were common. He reported that excessive levels of endocannabinoids could also be damaging for health, potentially leading to obesity and hepatic fibrosis.

Regulation of the endocannabinoid system is probably not be as simple as taking a dose of CBD or THC. There are dozens of cannabinoids in hemp and cannabis. Research indicates that whole-plant tinctures can be preferable to isolates of just one chemical. Given that endocannabinoid imbalances differ from patient to patient, the ideal medication for these imbalances may vary too. Perhaps someday, these treatments may be more be tailored to fit a person’s exact illness.

It’s clear we still have a lot more to learn about the endocannabinoid system before we can fully understand how it contributes to our health and well-being.

 

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Cannabinoid Antibiotics: How Hemp & Cannabis Could Help Fight Antibiotic Resistance

In recent decades, society has started to lose its battle against harmful bacteria. However, a new class of antibiotics could be developed in the future that are derived from naturally-occurring compounds found in hemp and cannabis.

Cannabinoid antibiotics could prove to be part of the solution to the threat of antibiotic resistance.

In recent decades, society has started to lose its battle against harmful bacteria. Not only are some types of bacteria becoming resistant to antibiotics, but researchers’ efforts to develop new classes of antibiotics have all but ground to a halt.

A study published in the British Journal of Pharmacology in 2011 noted that more than 20 classes of antibiotics were marketed between 1940 and 1962, however just two new classes have emerged since then. This wasn’t always a problem with the development of existing antibiotics proving enough to stave off the threat. Now, antibiotic-resistant bacteria are worryingly common, with gram-negative bacteria a particular concern.

A pharmacist in a lab coat examines bottles of medicine. Though research is only in its preliminary stages, doctors and pharmacists could someday prescribe cannabinoid antibiotics to their patients.

Though research is only in its preliminary stages, doctors and pharmacists could someday prescribe cannabinoid antibiotics to their patients.

However, it’s not all bad news. Preliminary research shows that one set of compounds could help manage the threat of bacteria, and even destroy superbugs such as methicillin-resistant Staphylococcus aureus (MRSA). Developed from hemp and cannabis, cannabinoid antibiotics could be in your future.

ANTIBIOTIC RESISTANCE IS BECOMING A ‘MAJOR GLOBAL THREAT’

It’s possible that we could have prevented our antibiotic crisis if we’d used them appropriately. Doctors and patients misuse antibiotics up to 50 percent of the time, according to estimates from the Centers for Disease Control and Prevention. Doctors aren’t always to blame for careless overprescribing. Patients sometimes pressure their GPs for antibiotics and some even self-medicate and buy antibiotics online.

However, there are no long-term benefits to taking antibiotics unnecessarily – even just as a precaution. Overprescribing and overuse just speeds up the rate that bacteria becomes resistant to antibiotics, which could lead to much more serious health issues, for the patient and the general public. The CDC estimates that every year there are more than 70,000 MRSA infections and 9,000 MRSA-related deaths in the US.

Ominously, former World Health Organization director general Dr Margaret Chan labelled antimicrobial resistance a “major global threat” in 2016, with the organization estimating that deaths from antibiotic-resistant infections could reach 10 million a year by 2050.

CANNABINOID ANTIBIOTICS TO THE RESCUE?

The antibiotic potential of cannabis, and therefore cannabinoids, was being studied as early as the 1950s, and the herb has a history of medical use dating back thousands of years to the times of ancient Egypt and ancient China. During the 1950s, cannabis sativa showed promising signs as an antiseptic, but with no individual components of the plant isolated at this stage, there was no way of telling which compounds were helping. It wasn’t until researchers began isolating cannabinoids in the 1960s that cannabis sativa really started to be understood.

Ground-breaking cannabinoid antibiotic research published in 2008 by Giovanni Appendino from the University of Eastern Piedmont and Simon Gibbons the University of London has developed our knowledge of cannabinoids as antibiotics significantly, although there’s still much we don’t know. Researchers aren’t quite sure why cannabinoid antibiotics work. Nor do they know how reliably those antibiotic effects would work in the body.

Most antibiotics target DNA gyrase or fatty acid synthesis, but cannabinoids appear to go after neither. Since the endocannabinoid system remained an unknown until the 1990s, it’s not unusual for us to be in the dark about how cannabinoids interact with the body, although given how effective these compounds are as antibiotics, they likely function in a specific mechanism, according to Gibbons.

A gloved hand holds a beaker containing amber liquid and a dropper, labeled CBD. Some research suggests CBD could be used as an antibiotic in clinical settings. Cannabinoid antibiotics represent the cutting-edge of research.

Some research suggests CBD could be used as an antibiotic in clinical settings. Cannabinoid antibiotics represent the cutting-edge of research.

Several non-psychoactive cannabinoids have displayed antibiotic properties, including cannabidiol (CBD) and cannabigerol (CBG). Psychoactive THC has been studied more extensively and appears to have some therapeutic effects that other cannabinoids haven’t yet shown.

CBD AS AN ANTIBIOTIC

Appendino and Gibbons found CBD to be effective against several types of MRSA. This included two strains that have been prevalent in British hospitals.

When CBD proved effective in treating these unusual strains, the researchers realized that cannabinoids might work differently from conventional antibiotics.

CBG, CBN and CBC AS ANTIBIOTICS

Appendino and Gibbons also noted CBG as a promising antibiotic in their 2008 paper. Cannabinol (CBN) and cannabichromene (CBC) also look to have potential. If scientists develop a cannabis-derived antibiotic, it’s likely to have greater success if it’s non-psychoactive.

With CBD, CBG, CBN and CBC all having antibiotic effects, development of an all-encompassing cannabinoid-based antibiotic may be possible. Scientists might derive these from whole-plant extracts of hemp.

THC AS AN ANTIBIOTIC

Despite being a psychoactive cannabinoid, you won’t get high if you apply THC to the skin. Therefore, it’s wide-ranging antibiotic prospects are likely to be of great interest to mainstream science.

Studies into the antibacterial effects of THC have been under way since at least the 1970s, with a paper in 1976 demonstrating that the cannabinoid was effective against both streptococcus and staphylococcus – the latter is responsible for the notorious staph infection. In this study, THC proved most effective in concentrations of 1 to 5 micrograms per millileter. However, scientists found THC (and also CBD) were not as helpful against these gram-negative bacteria in blood, leading many to dismiss the antibiotic uses of THC. Other tests also found THC to be ineffective against various types of gram-negative bacteria.

A hospital operating room. A hospital operating room. As antibiotic-resistant bacteria become danagerously commonplace, some researchers are turning to cannabinoid antibiotics made from cannabis and hemp.

As antibiotic-resistant bacteria become danagerously commonplace, some researchers are turning to cannabinoid antibiotics made from cannabis and hemp.

More recent studies are challenging this narrative. Whole-plant cannabis sativa oil has demonstrated antibiotic efficaciousness against Pseudomonas aeruginosa and E.coli, two types of gram-negative bacteria.

ROOM TO GROW IN CANNABINOID ANTIBIOTIC RESEARCH

More than anything, this revolutionary science is showing us what could be done with cannabis in the future if its properties are harnessed correctly. The emergence of CBD oil in recent times is another example of how cutting-edge science is broadening the plant’s appeal.

The research into cannabinoids as antibiotics is new and far from complete or confirmed. We are certainly not recommending using cannabis to self-medicate against antibiotic-resistant bacteria.

However, the early signs in this research are very intriguing. Cannabinoids seemingly bypass the mechanisms that other antibiotics use, and which bacteria have become wise to. If research continues in this vein, a doctor might someday prescribe cannabinoid antibiotics for you.

 

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Other Cannabinoids: There’s More Than Just CBD & THC In Hemp & Cannabis

You’ve heard of CBD and THC, but how well do you know cannabinoids like CBG, CBN and THCV? In this article, we investigate 3 other cannabinoids and their potential healing benefits.

You’ve heard of CBD and THC, but how well do you know cannabinoids like CBG, CBN and THCV?

The miraculous benefits of hemp are all the rage these days! With this huge surge in popularity for CBD and all it has to offer, it seems that everyday we are now learning about new cannabinoids that also show potential health benefits.

In this article, we’re going to touch on four of those cannabinoids, their unique medicinal benefits and their full spectrum properties in both industrial hemp and marijuana.

Since cannabinoids work better synergistically, rather than individually, it’s important to take the time to learn about all the different ways the compounds in hemp and cannabis work together.

A scientist studies a hemp plant in a field. Preliminary research into other cannabinoids reveals a host of possible healing benefits to naturally occurring chemicals like THCV and CBG.

The three we’ll discuss below are CBG (cannabigerol), THCV (tetrahydrocannabivarin), and CBN (cannabinol). Keep in mind that cannabinoid research is in its preliminary stages, but what we’ve already discovered is extremely promising.

So, let’s jump in!

CANNABIGEROL (CBG)

The first up in our study of cannabinodis is CBG (cannabigerol). Like CBD, CBG does not produce a “high” like THC does.

In fact, both THC and CBD start out as cannabigerol. It’s an interesting process. Basically, cannabis plants produce cannabigerol acid. Specific enzymes in the plant then breaks down the CBGA into the the acidic form of THC and CBD (known as THCA/CBDA). Next, THC and CBD form  as the acid burns off via decarboxylation.

CBG works by increasing anandamide levels. Anandamide is an endocannabinoid, a naturally occurring cannabinoid found throughout our bodies, that helps regulate biological functions including appetite, sleep, and memory.

CBG Benefits:

  • Cannabigerol stimulates bone formation and healing. In a study published on pubmed.gov, “Age-related osteoporosis is characterized by reduced bone formation and accumulation of fat in the bone marrow compartment. Here, we report that the type 1 cannabinoid receptor (CB1) regulates this process.” Results showed they could stimulate bone marrow stem cells by regulating osteoblast (bone formation) and adipocyte (fat accumulation in connective tissue) differentiation in marrow stromal cells.
  • Slows tumor growth! CBD, CBG, and CBC were all shown to slow the progression and growth of tumors and cancer cells. In a study published by cannabisinternational.org, CBG and other cannabinoids seem to have anti-proliferative/pro-apoptotic effects.
  • CBG has shown to have anti-fungal and antimicrobial properties, which make it a candidate for antifungal and antibacterial treatment. Some scientists believe CBG could be part of an effective treatment against MRSA (Methicillin-resistant Staphylococcus Aureus), a highly prevalent antibiotic-resistant strain of bacteria.
  • CBG is also showing promising results for treating overactive bladder, Psoriasis skin treatment, Glaucoma, depression and anxiety, and neuroprotective effects

TETRAHYDROCANNABIVARIN (THCV)

Next up is THCV (tetrahydrocannabivarin). The THCV compound makeup is very similar to the infamous THC cannabinoid, but it affects the body differently.

Both THC and THCV are psychoactive and will cause the user to get “high.” When THC binds to the body’s CB1 and CB2 receptors it activates them initiating the “high” effect. At low doses THCV also binds to those same receptors, but it does not activate them, behaving more like CBD. At higher dosages, THCV will activate the CB1 receptor much like THC and will produce a psychoative “buzz.”

Preliminary research into the various cannabinoids found in hemp and cannabis reveals that there's more to healing than just THC & CBD.

Preliminary research into the various cannabinoids found in hemp and cannabis reveals that there’s more to healing than just THC & CBD.

The feeling THCV produces seems to come on faster than THC and fades out faster as well. Users report a more clear-headed and stimulating high.

THCV Benefits, according to Leafly’s Bailey Rahn:

  • THCV may have anti-convulsive properties and can raise the seizure threshold for those with epilepsy. As a result, they experience fewer seizures.
  • Researchers are studying THCV’s ability to stimulate bone growth as a potential treatment for osteoporosis and other bone conditions.
  • THCV counteracts feelings of anxiety and shown to be effective in PTSD treatment.
  • Improves motor control, reduce tremors, and lessen the effects of brain lesions caused by Alzheimer’s disease. However it’s important to know that research is in the early stages and much more information is still needed.
  • Researchers believe THVC blocks the rewarding sensations we experience when eating, especially the unhealthy, comfort foods.

There is an informative article on THCV by Northwest Leaf called “THCV: A potent, rare and promising cannabinoid.” It’s a great read.

CANNABINOL (CBN)

The third cannabinoid to share is CBN (cannabinol). This is an interesting cannabinoid as it is produced when THC is heated or exposed to oxygen. Unlike THC, Cannabinol does not bind well to CB1 and CB2 receptors. Scientists classify CBN as non-psychoactive. CBN is not an abundant cannabinoid. The CBN content found in the cannabis plant on average will be less than 1 percent.

CBN Benefits:

  • Bone tissue growth. Studies show that CBN causes an indirect recruitment of mesenchymal stem cells that surround bone marrow. These stem cells are able to turn into bone and other tissues making it a possible candidate for healing bone fractures. The Journal of Neuroimmunology offers more information on this subject.
  • Like other cannabinoids, CBN is an anti-inflammatory cannabinoid that also has pain relief properties and preliminary research shows promise that CBN combined with CBD may prove to be an effective treatment for burns.
  • Sedative. According to a Royal Queen Seeds article, research shows that CBN can sometimes be as effective as pharmaceutical sedatives.
  • Scientists are also studying CBN as a possible sleep aid, an appetite stimulant, and as an anti-convulsive agent. CBN seems to work best symbiotically with CBD and THC.

CANNABINOIDS IN INDUSTRIAL HEMP VS PSYCHOACTIVE CANNABIS (‘MARIJUANA’)

Now that you have some knowledge of these cannabinoids, it’s important to understand how their profiles differ between industrial hemp and marijuana.

Both hemp and marijuana come from the cannabis plant, but different varieties and different growing methods differentiate high THC psychoactive cannabis (“marijuana”) from industrial low THC hemp plant. Both plants produce flower buds and both plants’ buds contain cannabinoids, but are the cannabinoids the same in both hemp and marijuana? The short answer is yes!

According to Franjo Grotenhermen, former Chairman of the International Association For Cannabinoid Medicines (2000-2003), “CBD is CBD.”

“The human body does not care where the molecule comes from,” Grotenhermen said.

A gloved scientist with a vial of CBD and a hemp leaf. 'Full spectrum' extracts contain more cannabinoids, terpenes, and other beneficial chemicals found in hemp & cannabis.

A gloved scientist with a vial of CBD and a hemp leaf. ‘Full spectrum’ extracts contain more cannabinoids, terpenes, and other beneficial chemicals found in hemp & cannabis.

Yet, there are distinct differences between the two. For example, psychoactive cannabis contains a high amount of THC, flavonoids and terpenes that hemp just doesn’t have. Marijuana also contains a higher concentration of cannabidiol than most forms of hemp.

‘FULL SPECTRUM’ MEANS MORE CANNABINOIDS, FLAVONOIDS & TERPENES

When consumers buy CBD that’s refined from industrial hemp, as in the majority of CBD products on the market today in the U.S., we always recommend purchasing a “full spectrum” extract. Full spectrum means that all of the cannabinoids, flavonoids, and terpenes found in the plant have been extracted and used in the CBD or hemp oil. Psychoactive cannabis can also be made into a “full spectrum” extract.

When a consumer ingests full spectrum oil, many scientists believe that it takes advantage of the “entourage effect.” This effect means that all cannabinoids, flavonoids, fatty acids, terpenes, and other plant compounds are working in concert with one another to maximize their benefits.

It is important to know that not everyone agrees that there is an entourage effect. According to Scientific American, “many scientists see the whole thing as a pipe dream. The idea that botanical marijuana creates synergistic chemical effect … is highly contentious.”

In general though, cannabis consumers and experts report a more satisfying, better healing experience from full spectrum products.

THC and CBD are the two most active cannabinoids in marijuana. They share a special synergy that contributes most to the entourage effect. While many people report benefits from low-THC, hemp-derived CBD extracts and full spectrum hemp oils. Others find they need the presence of THC for maximum effect.

CBD products made from hemp should be legal in all 50 states, while only portions of the U.S. currently have access to recreational or medicinal marijuana. We recommend trying everything that’s available to you to find out what works best for your needs.

THE SCIENCE OF CANNABINOIDS IS JUST GETTING STARTED

In conclusion, the study and research of cannabinoid compounds is still fairly new. While scientists have already made huge leaps forward, even bigger leaps into the cannabinoid world still await. As the United States slowly changes its cannabis laws and the popularity of CBD increases, it can only be uphill from here!

In the meantime, if you’re suffering from chronic pain, PTSD or other mental illness, or even osteoporosis, exploring other cannabinoids might offer additional relief. As with any treatment, please do your own research and consult a doctor.

 

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Dreaming On CBD: Will CBD Oil Cause Weird Dreams?

Because of CBD’s association with cannabis, new users wonder about the side effects of the supplement. Will CBD cause mind altering effects, for example? Or perhaps make you have weird dreams?

A lot of people wonder how CBD will affect their dreams, since bad dreams can be strange, disturbing and even scary.

Have you ever had a dream where all your teeth fall out? Lots of people have had it and the interpretations of what the dream actually means vary quite a bit. Some say it’s about change in your work life, others (like Carl Jung) suggest it’s related to feeling powerless. Whatever it means, it can be a pretty weird to have.

Sometimes these dreams are upsetting and, of course, unwanted. Because of its everyday association with cannabis, new users of CBD wonder about the side effects of the compound. Will it cause mind altering effects, for example? Or perhaps make you have weird dreams?

THC, CBD & DREAMS

Most of this comes down to a little confusion about CBD oil, and the differences between CBD and THC, the main active ingredient in marijuana. Because CBD does not get you high, and can even promote more restful sleep, CBD users are unlikely to experience these problems.

People mention cannabis and immediately get the wrong idea, thinking they’re going to get high from CBD. The main active ingredient in psychoactive cannabis or ‘marijuana,’ when it’s used for recreational purposes, is a chemical component in the plant called tetrahydrocannabinol or THC. Experienced users of THC products understand different strains and types of product can induce very unusual dreams.

CBD may promote restful sleep, and is less likely than THC to cause nightmares or other weird dreams.

Floating away into dreamland. CBD may promote restful sleep, and is less likely than THC to cause nightmares or other weird dreams.

In most reputable CBD products, you don’t get any of this because there’s no THC. That’s why the media sometimes CBD (mistakenly) refers to CBD as medical cannabis in places like the U.S.

CAN CBD OIL CAUSE WEIRD DREAMS?

Again, this is an area that generally needs a lot more research. First, it helps to know a little more about what happens when you drop off at night. Sleep has different, distinct stages. One well-known stage is REM or Rapid Eye Movement, This is where we normally dream or remember our dreams. The other stage, deep sleep, is beneficial for a lot of things including recovery and restoring the body. Think of it like recharging your batteries.

There have been some anecdotal accounts of people having weird dreams when using CBD, but these may not be down to the compound at all. Research into the effect of THC on sleep patterns found that it decreased the REM stage and increased the deep sleep phase. Subjects also reported a rebound effect when they stopped using the drug. Some people who stopped using CBD oil before bedtime also report having more vivid dreams.

Though more research is needed, it's unlikely that CBD will cause weird dreams.

A woman stretches out in restful sleep. Though more research is needed, it’s unlikely that CBD will cause weird dreams.

Other people have noted that their recall of dreams after taking CBD oil improves. Even if we do settle into REM sleep and dream, many of us don’t normally remember anything much when we wake up. There’s no evidence, clinical or anecdotal, that suggests any worsening of dreams such as nightmares or night terrors.

CBD COULD LOWER ANXIETY & PROMOTE RESTFUL SLEEP

Studies do suggest that CBD may be involved in lowering anxiety levels and many users point out they tend to fall asleep more quickly when using the compound. Some research also suggests that sleep quality may be improved which can lead to a better sense of feeling refreshed and higher energy levels on waking.

If you are worried about taking CBD for sleep issues or simply as a health supplement, there is currently little evidence to suggest that it is going to give you strange dreams during the night.

 

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