Best CBD Oil for Pain: Top 5 Brands in 2021 & Buyer’s Guide

Due to the incredible healing properties of some of cannabis plants’ chemical compounds, people have for centuries sought them out. But it was recently when one of its key compounds – a cannabinoid to be exact – drew the attention of both scientists and the common man. 

And that is CBD. This chemical compound is available in many forms like CBD Oil, Gummies, Creams in the market today. However, the most popular form is CBD oil, especially when it comes to combating painful and inflammatory conditions. 

It has been used for a ton of health conditions, including arthritis, chronic pain, osteoarthritis, and common inflammation of various parts of the body, including joints. 

Cannabidiol or CBD, as we commonly call it, is also reported to provide other health benefits, including better sleep, reduced anxiety, and improved immunity.

But not all CBD oil available in the market are good or genuine. Due to the growing demand for this compound, many wellness companies have entered the CBD industry. This abundance of options not only overwhelms a user but has also opened up the scope for many fake companies to abuse the trust of unwary customers.

That is why we continually keep you updated on the best and most effective, high-quality CBD products available in the market, which are safe, potent, and reasonably priced – so that you don’t get fooled by shrewd vendors trying to push useless or harmful products in the garb of “Authentic” or “Natural” CBD products. 

To select the best CBD oil for pain, we took several critical steps to ensure you get the best of everything. Here they are: 

  • We sought the opinion of some of the industry’s renowned experts, including researchers, testers, and long-time consumers. Their experience and understanding helped us select from around 50 brands of CBD oil brands in the market.
  • We also studied over 5,000 user reviews, including those on company websites, social media platforms, blogs, and open forums, to get a sense of how these brands have fared in the market.
  • We reached out to our readers through a survey, in which over 8,000 of our email subscribers gave their take on these different brands of CBD oil.
  • We took a closer look at each of their brand websites to check the veracity of some of the critical information needed to understand the brands and their products. These aspects included transparency, reliability, and sense of responsibility of the brands, the technology utilized by the brands, their farming, extraction, and manufacturing practices, etc. We also looked at their certificates of analysis (sent by third-party labs) to check their ingredients, safety profile, and cannabinoid content. 
  • Finally, we tested over 15 brands of the most recommended CBD oil brands to verify the authenticity of all their claims as well as to compare their quality and efficacy against their prices. We wanted to make sure that we only recommend brands that give you value for money.

5 Best CBD Oil for Pain

  1. FabCBD CBD OilTop Pick: Best Full-Spectrum & Flavors
  2. Cheef Botanicals Full-Spectrum CBD OilMost Effective & Best Value for Money
  3. CBDistillery CBD Hemp Oil – Affordable & Widest Variety
  4. NuLeaf Naturals Full-Spectrum Hemp CBD OilMost Potent
  5. Joy Organics CBD Oil Tinctures Best Broad-Spectrum CBD Oil

#1. Fab CBD Oil

Best Pick
FAB CBD Oil
  • 100% Organic
  • Wide Variety of Flavours
  • Free Shipping Above $89
  • 30 Days Money Back Guarantee


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Established with a vision to help people include CBD products into their everyday life, FabCBD caters to young adults keen on finding preventive measures to ailments and an overall wellness alternative to conventional medications. This online retailer goes above and beyond to keep its customers satisfied.

From its quality of CBD oil to its world-class customer service, from its excellent company policies to transparent manufacturing practices, organic farming, and CO2 extraction methods, this brand is the epitome of quality and safety in the industry. 

Besides, the brand’s CBD offerings are competitively priced and available in a variety of flavors and strengths. All products are non-GMO, organically sourced, and vegan.

Hemp Source:

Colorado, US

Extract type:

Full-spectrum CBD blend

Potencies:

  • 300mg
  • 600mg
  • 1200mg
  • 2400mg

Container size:

30ml

Flavors:

  • Citrus
  • Mint
  • Natural
  • Vanilla
  • Berry

Ingredients

  • Organic hemp extract
  • Full-spectrum cannabinoid blend 
  • Flavoring (natural sources like terpenes and essential oils) 
  • Medium Chain Triglycerides or MCTs (derived from fractionated coconut oil) as a carrier oil
  • May have trace amounts of THC (0.3%)

Lab Results:

ProVerde Labs 

Price range: 

  • 300mg: $39, i.e., $0.13/mg
  • 600mg: $59, i.e., $0.10/mg
  • 1200mg: $99, i.e., $0.08/mg
  • 2400mg: $129, i.e., $0.05/mg

Shipping Policy:

Free shipping in the US on all orders worth $89 and above

Return & Refund Policies:

30 days money-back guarantee, even if you’ve used a product (as long as you have not used up more than one of the same products).

Website Experience:

Easy-to-navigate, simple, clean, and informative

#2. Cheef Botanical Full-Spectrum CBD Oil

Best Value
Cheef Botanicals CBD Oil
  • THC Free
  • 4 Potencies: 300-3000mg
  • Free Shipping on All Orders
  • 30 Days Money Back Guarantee
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Cheef Botanicals was created with 25 years of experience in the organic food market by a group of ‘health-conscious cannabis enthusiasts”. Their background in the organic food industry gave them an edge in establishing Cheef Botanicals as a company offering high-quality organic CBD products. 

They back up the quality of their full line of organic, non-GMO CBD Oil with a money-back guarantee.

Cheef Botanicals addresses the need for a safe alternative in the wellness industry through its high-quality, all-natural, and affordable products as well as impeccable customer policies. 

This California-based company brings a holistic approach to retail CBD. They safely, naturally, and ethically source their CBD and manufacture their products and take dietary restrictions seriously. This brand only uses hemp grown in the United States for making its products. 

Besides, its products are vegan, cruelty-free, gluten-free, non-GMO, and dairy-free. Despite in huge variety in offerings, its products don’t come with any frills or gimmicks. You want CBD, you get CBD. Period. 

Hemp Source:

Colorado, US

Extract types:

Full-Spectrum (broad-spectrum hemp extract, as the extracts are THC-free)

Potencies:

  • 300mg
  • 600mg
  • 1200mg
  • 3000 mg 

Container sizes:

  • 15ml (300mg and 600mg)
  • 30ml (1200mg)
  • 60ml (3000mg)

Flavors:

Unflavored

Ingredients

  • Hemp seed oil
  • CBD-rich full-spectrum hemp extract

Lab Results:

CannaSafe

Price range: 

  • 300mg: $24.95, i.e., $0.08/mg
  • 600mg: $35.95, i.e., $0.06/mg
  • 1200mg: $66.95, i.e., $0.06/mg
  • 3000mg: $124.95, i.e., $0.04/mg

Shipping Policy:

Free shipping on all orders

Return & Refund Policies:

30-day money-back guarantee, plus a 15-day grace period, but only on unopened items in their original packaging.

Website experience:

Informative, well-guided, and professional-looking website, with ample information on the industry, CBD research, the brand’s products, as well as their dosage.

#3. CBDistillery CBD Oil

Affordable
CBDistillery Pure CBD Oil
  • All Natural
  • Wide Variety of Tinctures
  • 60 Days Moey Back Guarantee
  • Free Shipping over $75
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Established by an ambitious group of Colorado’s local entrepreneurs, CBDistillery is a brand Founded on the need for a safe and effective hemp-derived alternative for conventional medications. Their sole purpose is to make CBD accessible at affordable prices. 

You should consider CBDistillery if CBD oil, devoid of additives and artificial flavorings, is your thing. All its ingredients are not only organically sourced, but also formulated in a way that makes it pure and safe for consumption by all. 

These CBD oil contain high levels of fatty acids, B-complex Vitamins, and 20 essential amino acids. Although it has trace amounts of THC, its levels are so low (within permissible limits of 0.3% by dry weight) that consumers can use them without having to worry about getting high. 

The brand makes sure to get all its products tested by third-party labs and make their results available on its website for everyone to check. 

Another impressive thing about this brand is its level of transparency about the products’ ingredients. The consumers know exactly what goes into each bottle of CBD oil. 

Hemp Source:

Colorado US

Extract Types: 

  • Full-Spectrum CBD Oil Tinctures 
  • Broad-Spectrum CBD Oil Tinctures 
  • THC-Free Pure CBD Oil Tinctures (isolates) 
  • CBG + CBD Oil (1:1) Tinctures 
  • CBN + CBD (1:3) Sleep Tincture 

Potencies: 

  • Full-Spectrum CBD Oil Tinctures: 500mg, 1000mg, 2500mg, 500mg
  • Broad-Spectrum CBD Oil Tinctures: 500mg, 1000mg, 2500mg
  • THC-Free Pure CBD Oil Tinctures (isolates): 500mg, 1000mg, 2500mg
  • CBG + CBD Oil (1:1) Tinctures: 1000mg, 2000mg 
  • CBN + CBD (1:3) Sleep Tincture: 150mg CBN + 450mg CBD

Container sizes:

30ml

Flavors:

Natural/Flavorless

Ingredients

  • Full-Spectrum CBD Oil Tincture:
    • Fractionated Coconut Oil (MCT)
    • Full-Spectrum CBD Hemp Extract (Aerial Parts)
  • Broad-Spectrum CBD Oil Tincture:
    • Fractionated Coconut Oil (MCT)
    • Broad-Spectrum CBD Hemp Extract (Aerial Parts)
    • Natural Terpenes
  • THC-Free Pure CBD Oil Tincture (Isolates):
    • Fractionated Coconut Oil (MCT)
    • Cannabidiol (CBD) from Hemp Extract (Aerial Parts)
  • CBG + CBD Oil (1:1) Tinctures 
    • Full-Spectrum Hemp Extract (Aerial Parts)
    • Cannabigerol (CBG)
    • Fractionated Coconut Oil (MCT)
    • Natural Terpenes
  • CBN + CBD (1:3) Sleep Tincture 
    • Full-Spectrum Hemp Extract (Aerial Parts)
    • Cannabinol (CBN)
    • Fractionated Coconut Oil (MCT)
    • Natural Terpenes

Lab Results:

Available only after you’ve purchased a product and scanned the QR code provided on the product label. Alternatively, you can look it up on their website with the Lot No. 

Price Range: 

Full-Spectrum CBD Oil Tinctures: 

  • 500mg: $35, i.e., $0.07/mg
  • 1000mg: $60, i.e., $0.06/mg
  • 2500mg: $130, i.e., $0.05/mg
  • 500mg: $240, i.e., $0.05/mg

Broad-Spectrum CBD Oil Tinctures: 

  • 500mg: $32, i.e., $0.06/mg
  • 1000mg: $55, i.e., $0.055/mg
  • 2500mg: $120, i.e., $0.05/mg

THC-Free Pure CBD Oil Tinctures (isolates): 

  • 500mg: $32, i.e., $0.06/mg
  • 1000mg: $55, i.e., $0.055/mg
  • 2500mg: $120, i.e., $0.05/mg

CBG + CBD Oil (1:1) Tinctures: 

  • 1000mg: $75, i.e., $0.08/mg
  • 2000mg: $125, i.e., $0.06/mg

CBN + CBD (1:3) Sleep Tincture: 150mg CBN + 450mg CBD: $60, i.e., $0.13/mg of CBD

Shipping Policy:

Free shipping offered on all domestic orders worth $75 and above. 

Return & Refund Policies:

A 60-day satisfaction guarantee or full-refund guarantee for first-time purchases of any product; applicable only if products are purchased from their website.

Website Experience:

Simple layout, easy-to-navigate, engaging, and educative, with plenty of information on how to use their products, benefits of CBD, and the industry, at large. Besides, the variety of options for products, which is a plus. 

#4. NuLeaf Naturals Full-Spectrum Hemp CBD Oil

Nuleaf Naturals CBD Oil
  • Wide Variety of Potency from 300 to 6000mg
  • 30 Days Refund Policy
  • Naturally Made
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To maintain optimal strength, effects, and potency, NuLeaf Naturals provides a limited variety of products that are pure, natural, and safe. 

Sourced from Colorado’s licensed farms, the brand’s hemp extracts don’t contain pesticides, herbicides, or GMO, and is free of preservatives, additives, fillers, and all things considered as frills in the CBD industry. In other words, their CBD oil is all 100% pure, clean, and highly reliable.

That is why NuLeaf’s CBD oil are one of the finest products that there are in the market. 

Their CBD oil is tested by third-party or independent labs. NuLeaf Naturals’ products contain only full-spectrum hemp extracts. Compared to CBD-only products, these provide more enhanced effects for pain- and inflammation-related medical issues like osteoarthritis.

Hemp Source: 

Colorado US

Extract type:

Full-spectrum hemp extract

Potency:

  • 300mg
  • 900mg
  • 1800mg
  • 3000mg
  • 6000mg

Comes in bottles of varying sizes (each offering 60mg/ml CBD strength)

Container sizes:

  • 5ml
  • 15ml
  • 30ml
  • 50ml
  • 100ml

Flavor:

Natural

Ingredients

  • USDA-Certified Organic Virgin Hemp Seed Oil 
  • Full-spectrum hemp extract

Other cannabinoids, such as CBG, CBC, CBDA, CBDV, and THC (below 0.3% by dry weight) may also be present.

Lab Results:

Botanacor Laboratories 

Prices: 

  • 300mg: $38.50, i.e., $0.13/mg
  • 900mg: $99, i.e., $0.11/mg
  • 1800mg: $179, i.e., $0.10/mg
  • 3000mg: $239, i.e., $0.08/mg
  • 6000mg: $439, i.e., $0.07/mg

Shipping Policy

  • Fast (2 – 3 business days) 
  • Faster alternative, i.e., Express Mail (1 – 2 business day(s))
  • Free shipping (USPS Priority Mail) within the US

Return & Refund Policies:

30-day complete refund only on unused and sealed products; only the return shipping cost must be borne by customers.

Website Experience:

Simple yet effective and easily navigable layout with little fancy work – just like their products. The site also provides ample information on products and the industry at large.

#5. Joy Organics Broad Spectrum CBD Oil Tincture

Joy Organics CBD Oil
  • Wide Variety of Flavours
  • 0% THC
  • Free Shipping on All Orders
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Inspired by her personal loss and medical health conditions, Joy Smith founded Joy Organics as an alternative to conventional medications. She realized that CBD works where other medications fail. Driven by her experiences and her will to help others like her, she set up a retail store with her husband Todd back in 2018. 

Since then, this family-owned and operated business has made much headway in helping people from all over the world overcome pain and anxiety (just like her) through their CBD products that are available both on their online store and local retail store all over America. Their CBD oil is organic, pharmaceutical-grade, and clean hemp products.

Most of Joy Organics’ products are THC-free, with a few new full-spectrum variants for those who need a lot of the entourage effect. 

Hemp Source:

Colorado US

Extract type:

Broad-spectrum 

Potencies: 

  • 450mg
  • 900mg
  • 1350mg

Flavors: 

  • Natural Unflavored
  • Tranquil Mint
  • Orange Bliss
  • Summer Lemon

Ingredients

  • Natural Hemp
    • Organic Extra-Virgin Olive Oil
    • Organic Phytocannabinoid-Rich Hemp
  • Tranquil Mint 
    • Organic Extra-Virgin Olive Oil
    • Organic Phytocannabinoid-Rich Hemp
    • Organic Peppermint Essential Oil
  • Summer Lemon
    • Organic MCT
    • Organic Phytocannabinoid-Rich Hemp Extract
    • Organic Lemon Essential Oil
  • Orange Bliss
    • Organic MCT
    • Organic Phytocannabinoid-Rich Hemp Extract
    • Organic Orange Essential Oil

Lab Result

Depending on the batch number and form of the extract, the brand’s products are tested by different labs like:

  • PIXIS Labs
  • Green Scientific Labs
  • Botanacor Services
  • Cloud Labs
  • PhytaTech Metrics & Solutions

Price Range:

$0.08 – $0.13 per mg

Shipping Policy:

Free shipping on all orders

Return & Refund Policies:

30-day full-refund guarantee on all products.

Website Experience:

Professional-looking, easy-to-navigate, and educational.

Selecting The CBD Oil Brands for Pain: Critical Factors

  • Hemp Source: CBD oil comes from hemp plants, as they have low tetrahydrocannabinol content (THC; the psychoactive component of cannabis plants, high levels of which are present in marijuana). Where and how hemp is cultivated determines the quality of the extract. Hemp plants, grown in the US (and parts of the EU), are safer and more potent, as they are grown under strict guidelines, bound by federal regulations. They are generally organically grown, contain very little THC (<0.3%), and contain no harmful chemicals, GMO, or heavy metals. The US Hemp Authority is the regulatory body for all extracts derived from US-grown industrial/agricultural hemp.
  • Extract Types: Hemp extracts are generally of three types, i.e., full-spectrum hemp extracts that contain all plant nutrients of cannabis (cannabinoids (including traces of THC), terpenes, flavonoids, fatty acids, minerals, vitamins, and proteins), broad-spectrum extracts that contain all the same components of cannabis plants, except THC, and CBD isolates that contain only pure CBD extract. While the two former types are known to provide the entourage effect, people who need to undergo regular drug tests prefer the isolate CBD extracts. 
  • Potency: The CBD content is the most important part of assessing a CBD product’s standard. Usually designated in milligrams (mg), this is what directly determines the tincture’s efficacy. The more concentrated the oil, the more effective it is. That does not, however, mean that you take more CBD than you need. This is to help you determine your dosage. Reputed brands clearly mention their CBD content in their label. So, you can dose yourself properly. Admittedly, a person needs higher doses of CBD for pain compared to mental issues like anxiety and depression. However, taking too much does you no good. This is why the brands offer variations in CBD concentration. The effect of CBD does not depend on potency alone. A 25mg full-spectrum CBD oil could be more effective than a 100mg CBD isolate. So, it is best to start with a low dose. 
  • Container Size Variants: This is another way that brands help you dose better, i.e., by giving you variations in container sizes. Brands often provide variations like 15ml, 30ml, and 60ml in CBD oil with varying CBD concentrations. This means you can consume it at different times at different dosages as per requirement. 
  • Ingredients: Besides CBD, the other ingredients also play an important role in the product’s ultimate effect. Check out the ingredients and their quantities to know more about the product’s formulation, the combination of ingredients, and the overall quality. Ingredients like carrier oil, flavorings, and add-ons are meant to enhance CBD’s effects and help its easy absorption. Besides, reputed brands ensure to exclude all contaminants, synthetic chemicals, and high levels of THC from their hemp extracts. Always choose CBD oil made from naturally sourced ingredients, better still, from organically grown ones and those that are devoid of potential allergens.
  • Taste/Flavor: Although it may seem like a non-issue, aroma or flavor play a significant role in managing the overall experience, especially when someone is in extreme pain. Stimulation of our senses can help alleviate or exacerbate the condition. The more pleasant the taste, the better will be the user’s experience. While strong flavors could give you a headache, a bitter hempy flavor may dampen the experience. That’s why brands offer a range of delicious flavors to choose from. Additionally, natural and organic flavorings ensure a safer and better effect on the body.
  • Third-party lab test: A reputable, transparent company will take the responsibility towards their customers seriously. They would subject their products to third-party lab testing to confirm the products’ safety, efficacy, and due presence of necessary ingredients. In other words, independent laboratories can testify in an unbiased manner to the quality, safety, and content claims made by a CBD brand with scientific evidence. Do not buy from a CBD brand that hasn’t been reviewed by an independent lab.
  • Brand Reputation: Because the CBD industry is relatively new and the Food and Drug Administration doesn’t regulate all CBD products, a customer needs to consider the reputation of a company before purchasing their products. This is how you can find out whether the CBD oil brand values their customers and their feedback on what they sell.
  • Transparency: Companies that are keen on revealing their business practices publicly are open to discussions and customer opinions. Information on the farming practices, manufacturing, extraction, their technology, and the testing processes, along with independent lab results instill a sense of reliability among consumers.
  • Customer Service: Customer support is critical to ensuring happy customers. This maintains the brand’s reputation. Since this is the first and last line of engagement with the customers, a brand makes sure that it is at least as good as the products themselves, if not better.
  • Company Policies: The shipping, return, and refund policies must be customer-centric, especially in a competitive market like the CBD industry. Given the high prices of CBD products, free shipping, confirmed delivery, easy returns, and money-back guarantees are important to stay on in the business. 
  • Online Shopping Experience: A brand website must be easy to navigate, should provide ample information on the benefits of their products, offer easy shopping and checkout experience to make the overall shopping experience better.

How To Detect a Quality Brand?

Method of manufacturing

There are several methods that can be used to manufacture CBD products. But not all are made equal. Some are perfectly safe, and others may be risky due to the use of toxic solvents.

While CBD may offer pain relief, knowing how to pick the best CBD oil for pain can be confusing. Photo: An older woman helps an older man who is clutching his back in pain.
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While CBD may offer pain relief, knowing how to pick the best CBD oil for pain can be confusing.

The most reputable companies tend to use CO2 supercritical/subcritical extraction because it is one of the best ways to get a high yield of CBD without any exposure to toxic chemicals. It’s really the gold standard as far as CBD extraction goes.

When looking for a CBD oil product for your pain relief, ensure that the brand is transparent about its production process. If there’s little to no information is available, this is usually a huge red flag.

Third-party tested

Top tier CBD oil brands will usually boast that their products have been third-party lab tested. It’s a great selling point and helps to bring validity and transparency to the brand.

For the consumer, it also provides some reassurance that what is claimed on the label is accurate, and that the item is safe for consumption. So, before you purchase that CBD tincture to relieve your pain and other symptoms, make sure that the item has been third-party verified. The actual results of the test should be available for customers to review. When you’re examining this information, ensure that it’s up to date and that the tests have been conducted within the last 6 months.

Any brand of CBD oil should be third-party lab tested to ensure purity and reliability. Photo: A scientist in gloves and a white lab coat examines a test tube of green liquid, with a microscope nearby.
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Any brand of CBD oil should be third-party lab tested to ensure purity and reliability.

Usually details of the lab tests can be found on the company’s website. If they’re not available online, you should always request them from customer support.

Ingredients on the label

Transparent product labelling is absolutely essential for any consumable good. After all, you need to know exactly what you’re putting into your body.

There’s no way to tell if a CBD product is the best suited for your pain solely based on the nice graphics on the label. But the list of ingredients and nutrition facts on the back will certainly go a long way. The two main components that are usually included in a tincture are CBD and a carrier oil like MCT (often based on coconut oil) or hemp seed oil. Apart from that, you may observe fractional percentages of other cannabinoids on the lab test results.

Some brands may also offer their own special blend of herbs in addition to CBD, to enhance pain relief. Reputable companies usually give a detailed breakdown of all the ingredients included, and their respective percentages. If this information is obscure or non-existent, then we recommend you proceed with caution.

Reviews and recommendations

The internet makes it possible for us to get an idea of how a product will work before we make any monetary investment. Reviews and recommendations go a long way when shopping for CBD oil. Every brand will claim to provide the best CBD products for pain and the world of symptoms.

So, it helps to look beyond the marketing pitch and listen to the opinions of actual consumers or trustworthy sources. Always look for reviews and recommendations online before making a purchase. If the reviews are good then it will most likely be a good product, and if they’re bad, then you just saved yourself a bad experience.

In addition to sites like Ministry of Hemp, we often recommend the CBD subreddit on Reddit as a great resource for connecting with other CBD consumers.

Based on medical research, CBD can help get relief from pain, associated with different kinds of medical conditions. Some of them are elaborated here: 

Arthritis 

Arthritis Foundation’s recent survey found that 29% of their respondents used CBD, most of whom seemed to have benefited from its use. While scientists are still studying the veracity of CBD’s efficacy in combating arthritic pain, some studies have found promising results. In animal studies, nevertheless, CBD has been found to possess anti-inflammatory and pain-relieving properties, without posing any threat or side effects. 

Chronic Pain

Unfortunately, chronic pain affects a large majority of people all over the world at some point in their lives. Although opioids are usually used to relieve pain, they have many adverse effects and even tend to cause dependence and addiction. CBD is proposed as a better and safer alternative to opioids for pain relief.

Migraine

A painful condition, migraine is usually caused by stress, anxiety, and other chemical imbalances within the body. Tests, using a combination of CBD and THC, have shown that people can get relief from migraines and improve their body’s overall capacity to manage pain. In subjects in such a test was seen to experience relief from acute pain by as much as 55%. Additionally, the frequency of migraine attacks was also reduced by 40%. 

Cancer Treatment & Associated Issues

Both the effects and treatment of cancer are painful for patients. CBD has been found to be effective in lowering both these types of pain. To reduce the effects of cancer chemotherapy, such as pain, vomiting, and lack of appetite among patients, the National Cancer Institute also recommends the use of CBD. It has also been proven effective in getting better pain relief than opioids, without the side effects associated with opioid use.

Multiple Sclerosis (MS)

MS is an autoimmune disease that affects a patient’s nervous system, and thereby his/her entire body. People with MS experience extremely painful muscle spasms and a lack of control over their voluntary muscles. CBD oil use can reduce a person’s spasticity associated with MS. 

How CBD Interacts With The Body?

All cannabinoids impact the body by interacting with the endocannabinoid system. While studies on how it does that are still underway, we do know that cannabinoids like CBD and THC interact by binding directly or indirectly with some of the body’s cannabinoid and non-cannabinoid receptors of the body (quite like the endocannabinoids found within the body). 

Research on CBD’s Pain-Relieving Properties

  • According to a 2018 research by the National Center for Biotechnology Information, published in the Cannabis and Cannabinoid Research journal, nearly 62% of the people consuming CBD had a medical condition they were trying to treat. As per the study, among all the different medical conditions, the 3-most common medical conditions CBD is generally used for are to treat pain, anxiety, and depression.
  • As per the National Centers for Complementary and Integrative Health, there is evidence to indicate that cannabis compounds may have modest chronic pain benefits. 
  • According to a 2004 study, published in the British Journal of Pharmacology, CBD can relieve pain and inflammation in rat models through TRPV1-receptor-stimulation.
  • A 2017 review found that CBD helps treat chronic human neuropathy. Researchers examined 11 randomized controlled trials that included 1,219 patients to test the veracity of the claims.
  • According to a 2020 review, CBD may benefit patients with crippling and chronic pain, sleep disturbances, and chronic inflammation. However, the scientists stressed the need for more scientific data to determine CBD’s therapeutic effects and assess its exact efficacy and safe dosage.

CBD Shows Significant Pain Relief Potential in Scientific Studies

Numerous scientific studies suggest CBD can help with many different forms of pain. In a Feb. 2003 study published in Clinical Rehabilitation, a team of researchers from Oxford examined the benefits of CBD, THC, and a combination of both in patients who suffered from “neurogenic” pain (meaning their pain originated in their nervous system).

Most of the 24 patients in the study suffered from multiple sclerosis, but others had pain from spinal cord injuries or limb amputation. The study’s subjects regularly took one or more of the substances, or a placebo, at home, for two weeks while periodically reporting into the clinic.

“Pain relief associated with both THC and CBD was significantly superior to placebo,” the researchers’ wrote. Not only did the patients experience significant relief, but in some cases other unpleasant symptoms like muscle spasms were also alleviated.
 

cbd could help with chronic pain
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Another study, published in Oct. 2006 in Current Medical Research and Opinion, also supported the idea that cannabis extracts, including CBD, are especially effective in treating pain caused by multiple sclerosis. The authors looked at six different studies and found they consistently showed “Cannabinoids … are effective in treating neuropathic pain in MS.”

In March 2008, Ethan Budd Russo, a doctor in the Department of Pharmaceutical Sciences at the University of Montana, also found that CBD and cannabis in all forms offer significant benefits in the treatment of “difficult to manage pain.” Rudd’s report, another “meta-analysis” of multiple studies, is especially interesting because he reported that cannabis extracts can offer significant benefits not just when ingested orally, but also when applied topically to the skin. Many consumers have similarly reported receiving relief from topical forms of CBD oil and psychoactive cannabis.

CBD Oil Offers Relief From Menstrual Cramps to Migraines

To get a wider look at CBD’s potential benefits, we also searched a variety of anecdotal reports found in blogs and message boards.

Pamela Hadfield, a co-founder of the medical cannabis site HelloMD, reported in July 2015 that she “started using CBD to manage chronic pain caused by crazy, intense migraines.” While pharmaceutical drugs left her feeling mentally hazy, CBD seems to offer her immediate relief with few side effects.

Similarly, in a discussion last month on Reddit, many Redditors reported CBD quickly eases their menstrual cramps, though the dosage needed varies a great deal from person to person. The Redditors also noticed that the quality of the CBD extract made a big difference in its effectiveness. The source and quality of CBD oil products are vitally important, as we reported last July on Ministry of Hemp, so research all hemp products before you buy them.

While many people with chronic pain benefit from CBD oil alone, others receive the most relief from a combination of CBD and THC, which unfortunately remains illegal in many parts of the U.S. For example, Donna Burch, the author of the Fed Up With Fatigue blog, suffers from fibromyalgia, a poorly understood condition that combines debilitating fatigue and insomnia with severe muscle cramps. Burch reported in Sept. 2015 that while CBD oil seemed to help her pain for a while, it became less effective over time.

She ultimately found the most relief from psychoactive cannabis after receiving a permit for legal medical use. In states with medical cannabis programs, many chronic pain patients like Burch seek out strains bred to contain high levels of CBD along with THC.

CBD Dosage for Pain

The effects of CBD may vary from person to person. It largely depends on each person’s unique physiology, metabolism, the severity of the medical condition, form of CBD used, the formulation used by the brand, the purity of the extract used in the formulation, among several other factors. 

While not all factors can be controlled, like those that are in the hands of the companies making these products, certain things can be controlled by the users. 

Chronic pain and inflammation could cripple a person and jeopardize his/her normal life. unlike anxiety and depression, pain requires a lot more CBD, i.e., a larger dose. 

Broadly speaking, some of the patient-centric factors include:

  • Age
  • Gender
  • Bodyweight
  • Type of pain issues
  • The severity of the patient’s condition
  • The body’s capacity to absorb and metabolize cannabinoids
  • Mode of administration
  • Chemical balance within the patient’s ECS

Usually, a dose of around 2.85 to 50 mg/kg/day is usually therapeutic for and tolerable to humans. Nevertheless, it’s always safer to start with a small dose and gradually titrate the dosage. As soon as you reach the optimal dose, stick to it, without increasing it any further. 

Lastly, consult a medical practitioner before using CBD for the first time. Since you and your body are new to this substance, it is best to discuss the delivery method and dosage with a certified doctor before going ahead with self-treatment of pain with the help of CBD oil. 

Final Thoughts: Does CBD Oil Work On Pain Issues?

Although numerous studies have indicated CBD’s efficacy in treating pain, more research is needed, particularly advanced human trials. 

For now, we can state that the currently available research literature is promising, but not conclusive. Meanwhile, anecdotal evidence has been far more encouraging when it comes to chronic pain treatment. 

Due to the absence of the intoxicating effects and eventual side effects associated with THC (which is high in marijuana and low in industrial hemp), CBD oil sold by reputed brands have been found to be effective in helping people overcome painful conditions. 

Our list includes only those brands of products that have proven to be effective against painful health conditions by a large number of people worldwide. So, if you must use CBD for pain treatment, you can trust these brands to do right by you – in both helping you overcome pain and getting the most out of the money you shell out!

While CBD may offer pain relief, knowing how to pick the best CBD oil for pain can be confusing. Photo: An older woman helps an older man who is clutching his back in pain.
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Ministry of Hemp is America's leading hemp advocate.

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